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Senior Scientist - Protein Biochemistry


Enara Bio’s purpose is to shine a light on unconventional T cell targets to develop cancer immunotherapies designed to provide lasting benefit for broad patient populations. Our proprietary EDAPT™ platform enables us to discover a novel and differentiated class of cancer-specific targets from the genomic dark matter, which we call Dark Antigens™. We are pioneering approaches to exploit these Dark Antigen targets with a range of immunotherapeutic modalities, including bispecific T-cell engagers, adoptive cell therapies and cancer vaccines.
Enara Bio was founded in 2016 and has been well funded to invest in the build out and growth of our R&D efforts and our fantastic team. The company is based in Oxford, UK

Job Summary

We are seeking a motivated Scientist/ Senior Scientist with a passion for immunotherapy to join our newly established Protein Biochemistry function. This role requires technical expertise in in-vitro display and selection.

You will be expected to:

This is an opportunity for an innovative scientist to develop novel technology platforms and discover new therapies for cancers with significant unmet need.

Key Responsibilities

  • Helping to establish in-vitro display (yeast and mammalian) platforms and protocols required to engineer TCR-directed, bispecific T-cell engagers
  • Designing, conducting, and evaluating experiments to advance our preclinical pipeline of bispecific T cell engagers
  • Discussing data, seeking advice and providing expertise at cross functional team meetings to advance decisions and drive the future strategy
  • Ensuring scientific excellence is maintained within the Protein Biochemistry function
  • Actively contributing to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared among the teams

Minimum Qualifications and Experience required

  • Hands-on experience and technical knowledge of in-vitro display and panning platforms (ideally including yeast display)
  • Hands-on experience in molecular biology e.g. PCR, cloning, site-directed mutagenesis, and Sanger sequencing
  • A Ph.D. or equivalent scientific experience in a relevant discipline – e.g. molecular biology, biochemistry
    1. Senior scientist position will require 3+ years of relevant experience in scientific roles preferably within the biotech/pharma industry and a deeper technical understanding of the required skills
  • Excellent communications skills and a strong desire to work in a highly collaborative environment

Further information

The Enara Bio team is driven to make a meaningful difference for people affected by cancer. Our culture is defined by our behavioural ethos:

  • Act with unconditional positive regard and integrity
  • Support each other to grow and develop
  • Promote a collaborative, passionate and fun working environment
  • Innovate by discussing issues, data and ideas openly
  • Respect each other and value our diversity
  • Embrace our shared goals and take ownership of our journey

We offer a competitive salary, commensurate with qualifications and experience, and a benefits package including pension and health insurance.

Applicants should be able to demonstrate proof of the right to work in United Kingdom.
Enara Bio Limited is an equal opportunities employer.

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Job Reference: 1203660